Table 2.
Plasma proteins significantly up and down regulated after SIV infection. The average iTRAQ ratios (± standard deviation) from the six monkeys before and after SIV infection were used to compute the fold changes and significance (as determined by a paired student’s t-test). For significance, alpha was set at 0.05; since five tests were performed, using the Bonferroni correction a p value of <0.01 was necessary for reaching significance
| Protein identified | iTRAQ ratios pre-infection |
iTRAQ ratios post-infection |
Fold change |
p-value |
|---|---|---|---|---|
| Vitamin D binding protein |
0.59±0.31 | 0.93±0.27 | +1.57 | 0.006 |
| Histidine rich glycoprotein |
2.74±0.80 | 1.17±0.51 | −2.33 | 0.001 |
| Afamin | 2.14±0.59 | 0.77±0.20 | −2.77 | 0.003 |