FIGURE 1.

Confocal reconstructions of granule cell giant mossy fiber bouton complexes, which are comprised of a core giant bouton connected to one or more satellite boutons. A, An example of a giant mossy fiber bouton complex from a control animal. In controls, these complexes were rarely observed. B, Two days after status epilepticus, the incidence of giant mossy fiber boutons with satellites was increased 153% over control values (P = 0.049). C–E, One month after status, the percentage of giant mossy fiber boutons connected to satellite boutons was increased 461% over control values (P = 0.009). Scale bar = 3 μm. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]