TABLE 1.
2 Days control (N = 4) | 2 Days post-status (N = 6) | 1 Month control (N = 7) | 1 Month post-status (N = 12) | |
---|---|---|---|---|
MFB density (MFB per 100 μm) | 0.94 ± 0.12 | 0.91 ± 0.12 | 0.76 ± 0.06 | 0.61 ± 0.09 |
MFB with satellites (%) | 4.82 ± 2.39 (3 of 97)a | 12.19 ± 2.05* (12 of 102)a | 6.22 ± 1.72 (16 of 239)a | 34.92 ± 7.27** (63 of 254)a |
MFB area (μm2) | 8.21 ± 0.31 | 8.87 ± 0.75 | 7.94 ± 0.39 | 10.85 ± 0.73** |
Filopodia No. per MFB | 1.09 ± 0.27 | 2.34 ± 0.40* | 1.54 ± 0.26 | 3.41 ± 0.42** |
Average filopodia length | 2.35 ± 0.17 | 3.16 ± 0.40 | 2.08 ± 0.12 | 3.30 ± 0.24** |
Morphological measures from age-matched control and pilocarpine-treated mice examined 2 days and 1 month after status epilepticus. Values are means ± standard error.
Significant values are in bold.
MFB, giant mossy fiber bouton.
P < 0.05.
P < 0.01 (t-test).
Number of giant boutons with satellites relative to the total number of boutons examined. Note that percentages calculated from these numbers will differ slightly from percentages calculated from animal means.