TABLE 2.
24 h Control (N = 7) | 24 h Post-kindling (N = 7) | 1 Month control (N = 8) | 1 Month post-kindling (N = 7) | |
---|---|---|---|---|
MFB Density (MFB per 100 μm) | 0.65 ± 0.07 | 0.80 ± 0.06 | 0.70 ± 0.05 | 0.71 ± 0.04 |
MFB with satellites (%) | 7.76 ± 2.04 (13 of 154)a | 10.31 ± 2.42 (21 of 196)a | 5.63 ± 2.45 (10 of 193)a | 10.25 ± 2.16 (14 of 193)a |
MFB area (μm2) | 7.72 ± 0.71 | 11.46 ± 1.08* | 9.33 ± 0.60 | 9.47 ± 0.77 |
Filopodia No. per MFB | 1.11 ± 0.19 | 1.79 ± 0.23* | 1.61 ± 0.17 | 1.79 ± 0.18 |
Average filopodia length | 1.85 ± 0.17 | 2.59 ± 0.19* | 2.23 ± 0.18 | 2.30 ± 0.18 |
Morphological measures from control mice and age-matched kindled mice examined 24 h and 1 month after the last evoked seizure. Values are means ± standard error. Significant values are in bold.
MFB, giant mossy fiber bouton.
P < 0.05 (t-test).
number of giant boutons with satellites relative to the total number of boutons examined. Note that percentages calculated from these numbers will differ slightly from percentages calculated from animal means.