Figure 3.

Multiple alignment of conserved regions of the MJ0577 superfamily showing four sequence motifs. It was constructed by using psi-blast (38) followed by clustalw (39). The first column shows the protein identifier with the letters designating the organism code and the subsequent numbers designating the gene. Organism codes: MJ, M. jannaschii; MTH, Methanobacterium thermoautotrophicum; AF, Archaeoglobus fulgidus; BS, Bacillus subtilis; AQ, Aquifex aeolicus. Conserved residues are shaded. The black boxes below the sequence indicate conserved residues contacting ATP (A: adenine; R: ribose; P: phosphate; D: dimer interface). α-helices and β-strands are represented by brackets above the sequences. * at the C terminus designate those sequences with tandem homologs of MJ0577. Percent identities between the sequences are at far right.