Induction of apoptosis by over expression of U19/Eaf2, ELL, or both. A:U19/Eaf2 and ELL induce death in various cell lines. Indicated cell lines were transfected with U19-GFP or ELL-GFP. Cells expressing the fusion proteins were counted 3days after transfection. B: Co-expression of U19/Eaf2 and ELL result in enhanced cell death. Cells (293) were transfected with U19-GFP, RFP-ELL, or both.Percentage of dead cells expressing both proteins was counted. *, P < 0.05. C: Effect of MLL-ELL expression on U19/Eaf2-mediated cell death. Cells (293) were co-transfected with U19-GFP and MLL-ELL. Cells were counted 3 days after transfection. **, P < 0.01.