Table 1. Demographic and clinical characteristics of the SardiNIA cohort (overall, and stratified according to the phase of genotyping), and of the Old Order Amish study cohort.
| SardiNIA |
Old Order Amish | |||
|---|---|---|---|---|
| Overall | Initial GWAS | Stage 2 | ||
| N=6,049 | N=4,221 | N=1,828 | N=826 | |
| Age (years) | 43.7±17.6 | 43.1±17.4 | 44.1±16.9 | 46.4±15.1 |
| Sex (male) | 2569 (42.5%) | 1841 (43.6%) | 728 (39.8%) | 443 (53.6%) |
| Smoking (ever) | 1237 (20.3%) | 850 (20.1%) | 387 (21.2%) | 211 (25.5) |
| Height (cm) | 159.9±9.1 | 159.9±9.0 | 160.1±9.1 | 167.1±8.8 |
| Weight (kg) | 64.9±13.3 | 64.8±13.3 | 65.0±13.2 | 73.8±12.7 |
| BMI (kg/m2) | 25.3±4.7 | 25.3±4.7 | 25.3±4.6 | 26.4±4.3 |
| Systolic Blood Pressure (mmHg) | 125±18 | 125±18 | 125±18 | 120±15 |
| Diastolic Blood Pressure (mmHg) | 77±11 | 77±11 | 77±11 | 75±9 |
| Heart Rate (beats/min) | 67±11 | 67±11 | 68±11 | 64±9 |
| PWV (cm/sec) | 670±217 | 669±209 | 672±207 | 547±143 |
| Total cholesterol (mg/dL) | 209±43 | 208±42 | 210±42 | 210±47 |
| Triglycerides (mg/dL) | 88±68 | 87±68 | 89±69 | 72±44 |
| LDL (mg/dL) | 127±36 | 127±35 | 127±36 | 139±42 |
| HDL (mg/dL) | 64±15 | 64±15 | 64±15 | 56±15 |
| Fasting glucose (mg/dL) | 90±23 | 90±23 | 90±25 | 87±10 |
| Creatinine (mg/dL) | 0.8±0.2 | 0.8±0.2 | 0.8±0.2 | 0.8±0.2 |
| Antihypertensive medications | 752 (12.4%) | 544 (12.2%) | 208 (11.4%) | 18 (2.2%) |
Data are expressed as Mean±SD or N (%)