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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Hepatology. 2010 Jan;51(1):201–209. doi: 10.1002/hep.23279

Figure 2.

Figure 2

Forest plot showing odds ratios with 95% confidence intervals for the association with advanced fibrosis. Results of univariate and multivariable logistic regression are shown for the association of each of the following with advanced hepatic fibrosis (Ishak ≥ 3): caffeine consumption above the 75th percentile for the cohort (308 mg/day), coffee consumption >2 cups per day, caffeine and coffee consumption for HCV patients only (n=121) and caffeine consumption for patients reporting no change in caffeine intake in the past 5 years (n=119). Multivariable odds ratios are adjusted for age, sex, liver disease diagnosis, BMI, race and alcohol intake. Increased caffeine and coffee consumption are associated with a reduced risk of advanced fibrosis.