Table 1. Baseline Differences for Women With Cardiovascular Disease According to Aspirin Dose.
| No aspirin (n=4,827) |
81mg (n=1,224) |
325 mg (n=2,877) |
P value | |
|---|---|---|---|---|
| Demographics (%) | ||||
| Age ± SD | 66 ± 7 | 68 ± 6 | 68 ± 7 | <0.001 |
| Age | <0.001 | |||
| ≤60 | 23 | 12 | 15 | |
| >60 | 77 | 88 | 85 | |
| Race/Ethnicity | <0.001 | |||
| White | 75 | 83 | 84 | |
| Black | 16 | 9.0 | 9.8 | |
| Other | 9.6 | 7.8 | 5.8 | |
| BMI (kg/m2) ± SD | 29 ± 6 | 28 ± 6 | 28 ± 6 | <0.001 |
| BMI | <0.001 | |||
| <25 | 28 | 34 | 38 | |
| 25-30 | 38 | 35 | 27 | |
| >30 | 31 | 30 | 32 | |
| Clinical History (%) | ||||
| Diabetes | 15 | 14 | 16 | 0.334 |
| Hypertension | 58 | 60 | 63 | <0.001 |
| Systolic BP ± SD | 132 ± 19 | 132 ± 19 | 133 ± 19 | 0.022 |
| Diastolic BP ± SD | 75 ± 10 | 72 ± 10 | 73 ± 10 | <0.001 |
| Hypercholesterolemia | 28 | 45 | 43 | <0.001 |
| Stroke | 16 | 13 | 15 | 0.052 |
| TIA | 24 | 27 | 25 | 0.032 |
| Angina | 63 | 60 | 57 | <0.001 |
| Myocardial infarction | 21 | 26 | 31 | <0.001 |
| Percutaneous revascularization |
6.3 | 17 | 21 | <0.001 |
| Bypass surgery | 5.1 | 13 | 16 | <0.001 |
| PAD | 8.3 | 8.1 | 9.3 | 0.301 |
| CHF | 6.4 | 5.3 | 5.8 | 0.250 |
| Hormone use ever | 0.006 | |||
| Past user | 27 | 27 | 26 | |
| Current user | 39 | 44 | 41 | |
| Social History | ||||
| Smoking | 0.013 | |||
| Never smoked | 48 | 47 | 46 | |
| Past smoker | 44 | 47 | 47 | |
| Current smoker | 7.9 | 5.7 | 7.0 | |
| >7 alcoholic drinks/wk | 8.0 | 10 | 10 | <0.001 |
| Last medical visit w/in 1 year |
89 | 93 | 92 | <0.001 |
| Any Insurance | 96 | 98 | 97 | 0.001 |
| Medicaid | 5.5 | 2.3 | 2.9 | <0.001 |
| Medicare | 54 | 63 | 62 | <0.001 |
| Military / VA | 2.9 | 2.2 | 3.0 | 0.389 |
| Region | <0.001 | |||
| Northeast | 22 | 26 | 25 | |
| South | 28 | 22 | 24 | |
| Midwest | 21 | 20 | 24 | |
| West | 29 | 32 | 28 | |
| Education | <0.001 | |||
| < high school diploma | 10 | 6.5 | 8.5 | |
| high school – college | 61 | 58 | 61 | |
| ≥ college graduate | 29 | 36 | 30 | |
| Medications | ||||
| NSAIDs | 22 | 19 | 18 | 0.001 |
| Beta blockers | 18 | 28 | 31 | <0.001 |
| Statins | 15 | 31 | 30 | <0.001 |
CVD, cardiovascular disease; BMI, body mass index; BP, blood pressure; TIA, transient ischemic attack; PAD, peripheral artery disease; CHF, congestive heart failure; VA, veterans affairs; NSAID, non-steroidal anti inflammatory drug.