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. 2010 Jan;16(1):106–117. doi: 10.1261/rna.1894510

FIGURE 4.

FIGURE 4.

Comparison of the activities of L sshRNAs against two different targets. (A) Comparison of L sshRNAs specific for the same target as siRNA si72. SG118 and SG137 have a dinucleotide UU to link the antisense and sense strands (both are 19 nt in length). SG136 has a 19-nt antisense strand directly connected with the 5′ end of a 17-nt sense strand. (B) Comparison of L sshRNAs specific for the same target as siRNA si74. All three sshRNAs have dinucleotide UU as a connection between antisense and sense strands. Values labeled “as/s” represent the nucleotide lengths of antisense and sense strands.