Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of the activities of L sshRNAs with DNA substitutions in the duplex region. sshRNAs against the same target were compared for their potency of suppressing the expression of HCV IRES-fLuc reporter in 293FT cells. The sshRNAs with and without modifications were cotransfected in triplicate with the reporter DNA. Unmodified si19-3, specific for the same target, was used as a positive control.
