The five-way junction. (A) Networks of nucleobase stacking within the junction are illustrated with transparent space-filling models. The four major stacks are highlighted: (Purple) The T-loop stack, consisting of A33, G34, A245, A35, and C38; (green) the U37/G36/A247/G248 stack; (orange) the A25/U66-A121/A120 stack; and (gray) the A246/A122-G244 stack. (B) The five-way junction is also held together by a number of ribose zipper interactions, shown here in wall-eyed stereo.