Figure 2.

Samples of ipsilateral lumbar spinal cord from wild type, MKK3−/− and MKK6−/− naïve mice were immunoblotted on the same gel for direct comparison of p38 and P-p38 levels. All samples were normalized to β-actin and the y-axes on the histograms are in arbitrary units. In naïve animals, samples from WT mice contained less p38 than either MKK3−/− or MKK6−/− mice (p≤0.001). However, examination of P-p38 revealed no difference among any of the three strains. N=3