Figure 3.

Surface rendering of the three-dimensional reconstructions of actin filaments decorated with myosin AMIC. (a) constitutively active mutant, S329E, rigor state; (b) constitutively inactive mutant, S329A, rigor state; (c) constitutively active mutant, S329E, ADP-bound state. Also shown to allow direct comparison with other myosins I are BBMI reproduced from ref. 15 (d) and AMIB reproduced from ref. 17 (e). In each case, a filament segment containing approximately 14 molecules is shown along with a blow-up showing side views of the attached myosin I molecules. (Bar = 50 Å for blowups.)