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WNT/β-catenin signaling, inflammation, and myogenesis. Wnt signaling enhances β-catenin nuclear translocation, but inflammation promotes the formation of β-catenin/FOXO complexes, which divert β-catenin from forming a complex with TCF to induce myogenesis. DVL1L1, disheveled, dsh homolog 1; GSK-3B, glycogen synthase kinase 3; PP2A, protein phosphatase 2A.
