FIG. 6.
Pregnancy outcome of female B6C3F1 mice that were impregnated by either obese or lean male mice treated with either acrylamide (AA) or vehicle. A) Number of implants per litter determined in B6C3F1 mice. †Denotes statistical difference in the number of implants resulting from mating with obese males treated with vehicle vs. AA (P < 0.007). ††Denotes statistical decrease in the number of implants resulting from mating with AA- vs. vehicle-treated lean males (P < 0.0001). B) Number of live fetuses per litter determined in B6C3F1 mice. *Denotes statistical decrease in the number of live fetuses resulting from mating with AA-treated obese vs. lean males (P < 0.045). †Denotes statistical decrease in the number of live fetuses resulting from mating with obese males treated with vehicle vs. AA (P < 0.007). ††Denotes statistical difference in the number of live fetuses resulting from mating with lean males treated with vehicle vs. AA (P < 0.0001). C) Number of resorptions per litter determined in B6C3F1 mice. *Denotes statistical increase in the number of resorptions resulting from mating with AA-treated obese vs. lean males (P < 0.045). †Denotes statistical increase in the number of resorptions resulting from mating with obese males treated with AA vs. vehicle (P < 0.007). ††Denotes statistical difference in the number of resorptions resulting from mating with lean males treated with vehicle vs. AA (P < 0.0001). Data represents the mean ± SEM of 111 female mice per group.