Table 1.

Synaptic and Passive Properties of Motor Cortex Layer 2/3 Pyramidal Cells, Parvalbumin Interneurons and Striatal Medium Spiny Neurons from 3 Month Old Mice.

		Pyramidal Cells		Parvalbumin Interneurons		Medium Spiny Neurons
		WT	BACHD	WT	BACHD	WT	BACHD
EPSC	Frequency (Hz)	34.8 ± 7.4	36.4 ± 10.8	48.5 ± 15.6	54.9 ± 14.6	18.8 ± 9.7	13.9 ± 5.8
	Amplitude (pA)	16.0 ± 2.4	14.3 ± 1.6	15.5 ± 3.6	17.1 ± 2.7	15.3 ± 2.1	13.4 ± 2.5
	10–90 RT (ms)	0.72 ± 0.08	0.71 ± 0.09	0.55 ± 0.09	0.54 ± 0.05	0.70 ± 0.13	0.70 ± 0.07 #
	Decay (ms)	2.06 ± 0.82	2.30 ± 0.72	0.81 ± 0.34	0.64 ± 0.18 #	2.54 ± 0.36	2.87 ± 0.60
	IMean (pA/sec)	1.16 ± 0.33	0.99 ± 0.61	1.32 ± 0.40	1.60 ± 0.74 #	1.02 ± 0.23	0.78 ± 0.44 #
	n	10	9	13	12	11	14
IPSC	Frequency (Hz)	39.2 ± 10.9	38.6 ± 6.2	22.0 ± 10.4	24.4 ± 12.1	16.5 ± 7.0	11.0 ± 5.6
	Amplitude (pA)	30.5 ± 5.5	29.3 ± 8.5	27.6 ± 6.2	29.0 ± 9.8	31.7 ± 1.4	28.4 ± 5.8 #
	10–90 RT (ms)	0.90 ± 0.23	0.89 ± 0.19	0.72 ± 0.14	0.68 ± 0.09	0.80 ± 0.09	0.81 ± 0.10
	Decay (ms)	4.44 ± 1.00	4.57 ± 0.90	2.48 ± 0.62	2.33 ± 0.23 #	4.90 ± 1.14	4.82 ± 1.12
	IMean (pA/sec)	5.35 ± 2.54	5.62 ± 3.58	2.15 ± 2.22	1.89 ± 1.76	4.04 ± 1.27	2.94 ± 1.07
	n	8	10	12	9	8	11
Passive	Input Resist. (MΩ)	69.4 ± 28.9	76.2 ± 43.0	130.6 ± 58.6	112.1 ± 75.1	96.5 ± 63.9	104.6 ± 39.4
	τ(ms)	1.69 ± 0.45	1.89 ± 0.33	1.09 ± 0.21	1.25 ± 0.40 #	1.28 ± 0.17	1.47 ± 0.42 #
	Decay ratio	0.68 ± 0.05	0.70 ± 0.06	0.49 ± 0.17	0.38 ± 0.11	0.76 ± 0.07	0.79 ± 0.06
	N	12	10	13	12	12	16

^#Indicates a significant difference in the variance between WT and BACHD within the cell type (F-test, p ≤ 0.05)