Kinetics of protection against and mitigation of death induced by TBI by an HDAC inhibitor. The mean percentage increase in survival time in days is shown for groups of BALB/c mice receiving TBI and VPI at 400 mg/kg relative to survival time after TBI (7 Gy) alone. Error bars represent the range of survival times. n = 17, 32, 12 and 16 mice per group for 24 h before, 7 Gy alone, 1 h after, and 4 h after, respectively.