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. 2009 Aug 4;10(3):1065. doi: 10.1208/s12249-009-9294-2

Table III.

Data of the Skin Irritation Test

Rat Gp A Gp B Gp C Gp D Gp E Gp F
Er. Ed. Er. Ed. Er. Ed. Er. Ed. Er. Ed. Er. Ed.
1 0 0 3 2 0 0 0 0 0 0 1 0
2 0 0 3 2.5 0 0 1 0 1 0 1.5 0
3 0 0 4 4 0.5 0 0.5 0 0.5 0 1 0
4 0 0 4 3 1 0 1 0 1 0 0.5 0
5 0 0 4 2.5 0 1 0 0.5 0 0 0 0
6 0 0 3.5 2 1 1 0.5 0 1 0 1 0
Av. 0.00 0.00 3.58 2.67 0.42 0.33 0.50 0.08 0.58 0.00 0.83 0.00
SD 0.00 0.00 0.49 0.75 0.49 0.52 0.45 0.20 0.49 0.00 0.52 0.00
PII 0.00 ± 0.00 6.25 ± 1.24a 0.58 ± 0.49b,c 0.83 ± 0.52b,c 0.38 ± 1.01b,c 0.29 ± 0.65b,c

GP group, Er. erythema, Ed. edema, Av average, SD standard deviation, PII primary irritancy index

a p < 0.001 significant when compared to group A;

b p < 0.001 significant when compared to group B;

c p > 0.05 nonsignificant when compared to group A