Table III.
Rat | Gp A | Gp B | Gp C | Gp D | Gp E | Gp F | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Er. | Ed. | Er. | Ed. | Er. | Ed. | Er. | Ed. | Er. | Ed. | Er. | Ed. | |
1 | 0 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
2 | 0 | 0 | 3 | 2.5 | 0 | 0 | 1 | 0 | 1 | 0 | 1.5 | 0 |
3 | 0 | 0 | 4 | 4 | 0.5 | 0 | 0.5 | 0 | 0.5 | 0 | 1 | 0 |
4 | 0 | 0 | 4 | 3 | 1 | 0 | 1 | 0 | 1 | 0 | 0.5 | 0 |
5 | 0 | 0 | 4 | 2.5 | 0 | 1 | 0 | 0.5 | 0 | 0 | 0 | 0 |
6 | 0 | 0 | 3.5 | 2 | 1 | 1 | 0.5 | 0 | 1 | 0 | 1 | 0 |
Av. | 0.00 | 0.00 | 3.58 | 2.67 | 0.42 | 0.33 | 0.50 | 0.08 | 0.58 | 0.00 | 0.83 | 0.00 |
SD | 0.00 | 0.00 | 0.49 | 0.75 | 0.49 | 0.52 | 0.45 | 0.20 | 0.49 | 0.00 | 0.52 | 0.00 |
PII | 0.00 ± 0.00 | 6.25 ± 1.24a | 0.58 ± 0.49b,c | 0.83 ± 0.52b,c | 0.38 ± 1.01b,c | 0.29 ± 0.65b,c |
GP group, Er. erythema, Ed. edema, Av average, SD standard deviation, PII primary irritancy index
a p < 0.001 significant when compared to group A;
b p < 0.001 significant when compared to group B;
c p > 0.05 nonsignificant when compared to group A