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. 2009 Aug 12;10(3):1071. doi: 10.1208/s12249-009-9300-8

Table II.

Swelling Study

Formulation Time (h) Initial W t (W 0) (mg) Final W t (W t) (mg) Water uptake
Preliminary formulations
II (HPMC K4 M 30%) 2 204 403 97.54
4 201 561 178.910
6 196 689 251.53
8 298 791 299.49
III (HPMC K4 M 40%) 2 201 536 166.66
4 193 666 245.07
6 198 805 306.56
8 196 912 365.30
X (XG 30%) 2 205 519 188.29
4 193 678 251.29
6 195 787 303.54
8 199 865 334.67
XI (XG 40%) 2 196 598 205.10
4 198 752 279.79
6 205 834 306.82
8 201 901 348.25
XII (XG 50%) 2 201 659 227.86
4 206 881 327.66
6 199 1,051 428.14
8 201 1,189 491.54
Formulations of floating tablets
F I 2 305 819 168.52
4 291 752 293.12
6 293 823 348.80
8 294 901 413.60
F II 2 295 838 184.06
4 291 1,126 286.94
6 299 1,288 330.76
8 295 1,478 401.00
F III 2 289 811 180.62
4 299 1,094 265.88
6 304 1,259 314.14
8 297 1,426 380.13
F IV 2 294 804 173.46
4 293 1,096 274.06
6 299 1,303 357.78
8 302 1,491 393.70
F V 2 299 817 173.24
4 295 1,119 270.32
6 295 1,305 343.37
8 298 1,489 399.66

n = 3

HPMC hydroxypropyl methyl cellulose, F formulation