Table III.
In Vitro Dissolution Data of Tablet Formulations for Preliminary Trials
| Floating lag time (min) | Floating time (h) | Matrix integrity | T 50 ± SD (h) | T 85 ± SD (h) | |
|---|---|---|---|---|---|
| I | – | – | − | 0.38 ± 0.01 | 0.82 ± 0.01 |
| II | <1 | 24 | + | 2.8 ± 0.28 | 6.2 ± 0.1 |
| III | <1 | 24 | + | 4.4 ± 0.15 | 8.2 ± 0.05 |
| IV | – | – | − | 0.2 ± 0.005 | 0.4 ± 0.02 |
| V | – | – | − | 0.30 ± 0.02 | 1.1 ± 0.12 |
| VI | – | – | − | 0.29 ± 0.01 | 1.03 ± 0.06 |
| VII | – | – | − | 0.38 ± 0.01 | 0.38 ± 0.02 |
| VIII | – | – | − | 0.39 ± 0.01 | 0.38 ± 0.02 |
| IX | – | – | − | 0.43 ± 0.02 | 1.1 ± 0.1 |
| X | – | – | + | 4.9 ± 0.31 | – |
| XI | >1 | – | + | 8.2 ± 0.26 | – |
| XII | <1 | – | + | 10.1 ± 0.21 | – |
| XIII | <1 | – | − | 0.29 ± 0.01 | 0.91 ± 0.01 |
| XIV | – | – | − | 0.31 ± 0.01 | 0.88 ± 0.03 |
| XV | – | – | − | 0.31 ± 0.02 | 0.88 ± 0.02 |
SD standard deviation