. 2009 Jul 2;10(3):887. doi: 10.1208/s12249-009-9276-4

Table III.

Correlation Coefficients of Different Mathematical Models and Release Rate Constant (k) for Rosiglitazone Maleate Microspheres in Simulated Gastric Fluid

Formulation	Correlation coefficient (R ²)			k ^a (mg h^−0.5)
Formulation	Zero order	First order	Higuchi equation	k ^a (mg h^−0.5)
F1	0.7551	0.7927	0.9070	18.588
F2	0.8716	0.8847	0.9265	2.228^b
F3	0.9258	0.9386	0.9637	1.456^b

^a k was calculated based on the Higuchi model

^bRelease rate constant was calculated excluding first 2 h of burst release