Table IV.
Evaluation Studies of Cyclodextrin Complexes of Curcumin
| Code | Name of complex | Complexing agent used | Total drug (%)a | Solubility (mg/ml)a | |
|---|---|---|---|---|---|
| Ratio | Method | ||||
| Pure drug | Not applicable | 0.0030 | |||
| A-CD | (1:1) | CS | HP-βCD | 99.47 | 0.3830 |
| B-CD | (1:2) | CS | HP-βCD | 93.68 | 0.3819 |
| D-CD | (1:1) | KN | HP-βCD | 99.21 | 0.5526 |
| E-CD | (1:2) | KN | HP-βCD | 97.63 | 0.6086 |
| F-CD | (1:1) | CS | M-βCD | 99.21 | 0.4156 |
| G-CD | (1:2) | CS | M-βCD | 96.05 | 0.3191 |
| H-CD | (1:1) | KN | M-βCD | 95.79 | 0.4929 |
| I-CD | (1:2) | KN | M-βCD | 97.37 | 0.5891 |
CS common solvent evaporation method, KN kneading method
a±SD = average of three readings