Table III.

Dissolution Profile of IRB–βCD–PVP K-90 and IRB–βCD–PEG 4000 at Various Concentrations in 0.1 N HCl at 37 ± 0.5°C (n = 3)

Sample	% Drug dissolved
	5 min	10 min	15 min	20 min	30 min	45 min	60 min
IRB–βCD—2% w/w PVP K-90	86.78 ± 1.7	90.45 ± 2.3	93.23 ± 0.7	96.58 ± 2.2	98.41 ± 0.8	100.19 ± 1.6	100.19 ± 1.6
IRB–βCD—5% w/w PVP K-90	96.94 ± 1.8	99.698 ± 1.3	99.49 ± 2.1	100.41 ± 0.6	100.41 ± 0.6	100.41 ± 0.6	100.41 ± 0.6
IRB–βCD—10% w/w PVP K-90	96.31 ± 0.9	97.98 ± 1.7	99.31 ± 2.1	100.12 ± 0.1	100.12 ± 0.1	100.12 ± 0.1	100.12 ± 0.1
IRB–βCD—2% w/w PEG 4000	84.56 ± 0.8	87.63 ± 1.6	91.89 ± 1.9	93.32 ± 2.3	96.48 ± 0.7	99.23 ± 0.8	100.12 ± 1.8
IRB–βCD—5% w/w PEG 4000	85.23 ± 1.9	86.17 ± 1.1	89.61 ± 1.9	93.37 ± 2.3	97.97 ± 0.8	99.45 ± 1.6	100.87 ± 1.3
IRB–βCD—10% w/w PEG 4000	94.73 ± 0.7	96.12 ± 1.8	98.46 ± 2.0	99.91 ± 0.4	101.32 ± 1.6	101.32 ± 1.6	101.32 ± 1.6
IRB–βCD—15% w/w PEG 4000	95.64 ± 0.9	96.89 ± 1.8	97.56 ± 1.4	99.96 ± 2.1	100.12 ± 1.4	100.89 ± 0.8	100.65 ± 1.7