Skip to main content
. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1815–1820. doi: 10.1158/1055-9965.EPI-08-0983

Figure 1. A schematic view of genetic association between SNPs at 11q13 and prostate cancer risk in CAPS.

Figure 1

(a) Allele tests for 84 SNPs at 11q13 and prostate cancer risk in CAPS. Two separate clusters of prostate cancer associated SNPs were found (blue dotted boxes), including the previously reported locus 1 (rs10896449) and a novel locus 2. The blue diamond represents P-values of single SNP analysis and the pink diamond represents P-values after adjusting for rs10896449. (b) Inferred haplotype blocks of these SNPs were estimated from the control subjects in CAPS using the Haploview computer program. These two loci were in different haplotype blocks. (c) A recombination hotspot between the two loci using SequenceLDhot software. (d) mRNA at 11q13.