FIG. 1.

Human MUC1 and mouse Muc1 mRNA expression in early pregnancy. Endometrial extracts from Days 1, 3, and 4.5 postcoitum of Tg(MUC1)79.24Gend were obtained and analyzed for MUC1, Muc1, and Krt18 by real-time RT-PCR as described in Materials and Methods. Human MUC1 and mouse Muc1 mRNA expression were determined relative to that of mouse Krt18. The bars indicate the mean ± SD values from triplicate determinations of triplicate samples in each case and are expressed relative to Day 1. Note that although Muc1 expression declines almost to zero, MUC1 persists at approximately 20% of the level observed on Day 1.