FIG. 5.

Human MUC1 expression at the site of implantation. Sections of mouse implantation sites at Day 5 from wild-type and human MUC1 transgenics were analyzed by indirect immunofluorescence with anti-CT-1 (red), anti-214D4 (green), and draq5 (arbitrarily assigned the color blue) as described in Materials and Methods. Sections of an implantation site (A–D) from uteri of wild-type FvB expressing only mouse MUC1 were used as controls to compare to human MUC1 transgenic uteri sections (E–H). Human MUC1 expression persists at the site of implantation (E, F, and H) compared with mouse MUC1 expression (A, B, and D) which is lost at the site of implantation. Arrows indicate glandular epithelia. Bar = 100 μm.