Table 3.
Ranking of the incidence of simultaneous skewing in CD4+ and CD8+ T-cell subsets
Vβ | Number of Subjects Expressing Both CD4+ and CD8+ Skewed Vβs |
Association to S. aureus SAg’s |
|
---|---|---|---|
Strong | Weak | ||
17 | 4 (20%) | SEB, SEC2 | |
12 | 3 (15%) | SED | SEC1, SEC2, SEC3, SEG |
21.3 | 3 (15%) | SEQ | |
8 | 2 (10%) | SEE | SED, |
23 | 2 (10%) | SEA, SEI | |
3 | 2 (10%) | SEB, SEC1 | SEG |
5.2 | 2 (10%) | SEK | |
13.1 | 2 (10%) | SEC2 | SEG |
5.1 | 2 (10%) | SEI | SEC3, SEE, SEK, SEQ |
5.3 | 1 (5%) | SEA, SED | SEI |
2 | 1 (5%) | TSST1 | SEB, SEQ |
1 | 1 (5%) | SEA, SEB, SED, SEI | |
20 | 1 (5%) | SEC2 | |
14 | 0 | SEG | SEC2 |
13.2 | 0 | SEG | |
9 | 0 | SEA |
Table depicts the ranking of simultaneous skewing in 16 of 24 specific Vβs analyzed based on frequency. Both strong and weak S. aureus SAg associations are shown. Some subjects expressed more than one Vβ-skewing. In these 20 subjects, 7 (35%) had skewed distributions for one or more Vβ related to a strong SAg effect.
SE(A–Q) = Staphylococcal Enterotoxin (A–Q); TSST1 = Toxic Shock Syndrome Toxin-1.