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Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study (reproduced from Zarate et al.[55]). Tamoxifen vs placebo: * p < 0.05 after correction. Week vs baseline for tamoxifen: * p < 0.05, ** p < 0.01, *** p < 0.001 after correction. YMRS = Young Mania Rating Scale.
