Fig. 3.

Inhibition of the Na⁺ and the Ba²⁺ components by diclofenac. (A) Representative currents inhibited by drugs denoted above the right trace. With the application of diclofenac (100 µM), nifedipine (1 µM), or nickel (300 µM), reduced currents were shown on the right. The amplitudes of the initial transient component and the slowly decayed components were measured at the positions marked by the closed circle (●) and triangle (▲), respectively. (B) Summary of the normalized data for the effect of drugs on the two components. Relative inhibitions (%) of the Na⁺-sensitive initial transient and the nifedipine-sensitive components are shown in upper and lower panel with number of observations, respectively. Data were normalized to currents measured before application of each drug. Scale bars are equal to 1 nA and 50 ms.