Table 3.

Pharmacokinetic values for imatinib and its active metabolite, CGP74588, on day 8 of cycle 1 (ng/ml)

	Imatinib			CGP74588
	Pre	24 h	Cmax	Pre	24 h	Cmax
Mean	2,129	2,248	4,452	517	517	906
SD	1,600	1,408	2,421	326	275	409
Median	1,702	2,066	4,361	456	477	847
Minimum	596	626	1,942	210	183	323
Maximum	6,532	6,133	12,063	1,310	1,068	2,000

Abbreviations: Pre, day 8 pretreatment sample; 24 h, 24-h (day 9 pretreatment) sample; C_max, maximum plasma concentration.