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. 2009 Dec;11(6):853–860. doi: 10.1215/15228517-2009-010

Table 4.

Results of immunohistochemical studies

PDGFR-α Staining
PDGFR-β Staining
Specimen Tumor Cellsa Blood Vesselsb Tumor Cellsa Blood Vesselsb Response PFS (Months)
1 2+ Few 3+ Some PD 2
2 3+ All 3+ All SD 9
3 3+ Few 3+ Some SD 6
4 1+ All 1+ All PD <1
5 3+ Few 3+ Some SD 7

Abbreviations: PDGFR, platelet-derived growth factor receptor; PFS, progression-free survival; PD, progressive disease; SD, stable disease.

a

Expression-level intensity in tumor vessels: 1+, faint but distinct; 2+, strong; 3+, very strong.

b

Percentage of tumor cells expressing protein: few, less than 5%; some, 10%–20%; all, >60%.