Table 4.
PDGFR-α Staining |
PDGFR-β Staining |
|||||
---|---|---|---|---|---|---|
Specimen | Tumor Cellsa | Blood Vesselsb | Tumor Cellsa | Blood Vesselsb | Response | PFS (Months) |
1 | 2+ | Few | 3+ | Some | PD | 2 |
2 | 3+ | All | 3+ | All | SD | 9 |
3 | 3+ | Few | 3+ | Some | SD | 6 |
4 | 1+ | All | 1+ | All | PD | <1 |
5 | 3+ | Few | 3+ | Some | SD | 7 |
Abbreviations: PDGFR, platelet-derived growth factor receptor; PFS, progression-free survival; PD, progressive disease; SD, stable disease.
Expression-level intensity in tumor vessels: 1+, faint but distinct; 2+, strong; 3+, very strong.
Percentage of tumor cells expressing protein: few, less than 5%; some, 10%–20%; all, >60%.