Skip to main content
. 2010 Jan;38(1):133–142. doi: 10.1124/dmd.109.029371

Fig. 2.

Fig. 2.

Representative reverse-phase gradient LC-MS/MS MRM chromatograms of FLX-CoA from the analysis of extracts from untreated rat hepatocytes (A), rat hepatocytes incubated for 6 min with 100 μM (S)-(+)-FLX (B), rat hepatocytes incubated for 6-min with 100 μM (R)-(−)-FLX (C), and extract from rat hepatocytes spiked with (R,S)-FLX-CoA authentic standard (10 nM) (D). The LC-MS/MS MRM transition used for the analysis of FLX-CoA was MH+ m/z 1035 to m/z 528. The relative abundances for each trace on the y-axes are equal.