Table 3.
Unadjusted and adjusted Cox proportional hazards and 95% confidence intervals of all-cause mortality for 4,944 patients with complete data*
| Variable | Unadjusted HR | P | Adjusted HR | P |
|---|---|---|---|---|
| 6-month response | ||||
| Complete (ref) | 1.00 | 1.00 | ||
| Virologic-only | 1.46 (1.05 – 2.04) | .024 | 1.50 (1.08 – 2.09) | .015 |
| Immunologic-only | 1.51 (0.78 – 2.92) | .218 | 1.53 (0.90 – 2.58) | .111 |
| Absent | 4.56 (2.01 – 10.36) | <.001 | 5.43 (2.20 – 13.42) | <.001 |
| Baseline CD4 cell count (100cells increase/μL) | 0.85 (0.76 – 0.95) | .007 | 0.90 (0.71 – 1.13) | .373 |
| Age in years | ||||
| 16 – 29 (ref) | 1.00 | 1.00 | ||
| 30 – 39 | 0.99 (0.64 – 1.55) | .990 | 1.06 (0.65 – 1.72) | .820 |
| 40 – 49 | 1.18 (0.94 – 1.48) | .154 | 1.24 (0.85 – 1.82) | .266 |
| 50+ | 1.58 (1.02 – 2.48) | .041 | 2.00 (1.22 – 3.28) | .006 |
| Clinical stage | ||||
| Less advanced (ref) | 1.00 | |||
| Advanced | 1.04 (0.58 – 1.85) | .891 | ||
| Unknown | 1.04 (0.55 – 1.98) | .900 | ||
| AIDS defining event | 1.45 (0.91 – 2.30) | .115 | ||
| HAART Regimen | ||||
| NNRTI based (ref) | 1.00 | 1.00 | ||
| PI-based | 1.21 (0.87 – 1.67) | .243 | 1.57 (0.65 – 3.75) | .311 |
| Other | 0.71 (0.48 – 1.05) | .094 | 0.51 (0.22 – 1.20) | .123 |
*
Adjusted for year of therapy initiation and clinic as fixed effects