Table 2.

Distribution of gene changed during in vitro/in vivo retina development

	Early stage (fold)				Late stage (fold)
	>2	>3	<2	<3	>2	>3	<2	<3
Total	274	73	127	3	9	2	91	19
Adhesion	3	1	1	0	1	0	4	2
Angiogenesis	1	0	0	0	0	0	3	0
Apoptosis	3	0	2	0	0	0	2	0
Carbohydrate metabolism	0	0	1	0	2	1	2	1
Cell cycle	7	2	6	1	0	0	0	0
Chromatin	2	1	8	0	0	0	1	0
Cytoskeleton	7	1	3	0	0	0	7	2
Development	1	1	0	0	0	0	4	2
DNA metabolism	2	1	3	0	0	0	0	0
Exocytosis	0	0	0	0	0	0	1	0
Extracellular matrix	0	0	1	0	0	0	0	0
Immune response	4	1	0	0	0	0	2	0
Iron metabolism	1	1	0	0	0	0	0	0
Lipid metabolism	8	2	2	0	1	0	0	0
Migration	1	1	0	0	0	0	0	0
Neurotransmitter metabolism	9	1	3	0	0	0	10	4
Redox	3	2	8	1	0	0	0	0
Phototransduction	2	0	0	0	0	0	5	2
Pigment metabolism	0	0	0	0	0	0	1	0
Protein metabolism	8	1	4	0	0	0	1	1
Pyrimidine metabolism	0	0	1	0	0	0	0	0
Purine metabolism	1	1	0	0	0	0	0	0
RNA metabolism	0	0	4	0	0	0	0	0
RNA splicing	0	0	3	0	0	0	1	0
RNA binding	2	2	4	0	0	0	1	0
Signaling and transcription	28	1	19	1	0	0	9	2
Stress response	4	0	0	0	0	0	0	0
Transport	5	2	6	0	1	0	3	0
Ubiquitination	2	0	1	0	0	0	0	0
Unknown	170	51	47	0	4	1	34	3

Early stage, PN2–PN6; late stage, PN8–PN15