Table 1.

Effect of RI-knockdown on the Inhibition of Cell Proliferation by Ribonucleases (IC₅₀; μM)

		ribonuclease
Cell line		ONC	$\frac{{\text{IC}}_{50}^{\text{neg}}}{{\text{IC}}_{50}^{\text{pos}}}$	G88R RNase A	$\frac{{\text{IC}}_{50}^{\text{neg}}}{{\text{IC}}_{50}^{\text{pos}}}$	RNase A	$\frac{{\text{IC}}_{50}^{\text{neg}}}{{\text{IC}}_{50}^{\text{pos}}}$
HeLa	neg	0.9 ± 0.2	1.1 ± 0.4	67 ± 11	6.7 ± 1.1	>200	—
	pos	0.8 ± 0.2		10 ± 2		>200	—
K-562	neg	0.49 ± 0.07	0.96 ± 0.18	4.5 ± 0.6	4.6 ± 0.8	>200	—
	pos	0.51 ± 0.06		0.97 ± 0.09		>200	—
Hep-3b	neg	0.14 ± 0.03	1.1 ± 0.3	13 ± 2	4.3 ± 1.5	>200	—
	pos	0.13 ± 0.03		3.0 ± 0.9		>200	—