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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Gut. 2009 Nov;58(11):1546–1554. doi: 10.1136/gut.2009.179531

Figure 5.

Figure 5

MicroRNAs (miRNAs) as potential diagnostic biomarkers. Various aspects of miRNAs provide novel ways of utilising these in disease diagnosis. The unique miRNA signatures of different tumours distinguish the cancer from normal tissue. MiRNA classifiers can accurately identify the tissue of origin in the case of cancers of unknown primaries. Blood-based miRNA profiling as a diagnostic test provides a non-invasive and fast alternative to traditional methods. MiRNA patterns can also differentiate various tumour subtypes. Testing for miRNA-associated SNPs is another novel approach towards predicting cancer predisposition.