Figure 6.
Comparison of the lactulose to mannitol ratio at different times using the two formulations. Data show the geometric means and 95% confidence intervals. After liquid formulation, the ratio is higher at 8–24 hours than with all other urine samples. Note also that the ratio is higher for the urine samples after liquid and capsule formulations at 8–24 hours compared with 0–2 hours with the liquid formulation. These data suggest colonic (6–8 hours or 8–24 hours) permeability is higher than small bowel permeability (0–2 hours). There were no significant differences in ratios at 6–8 hours and 8–24 hours with either formulation, and there were no differences between the different formulations at these times.