Table 4.
Binding of human papillomavirus-16 short E6 peptides included into E6/2 (14–34) and E6/4 (45–68) to human leucocyte antigen (HLA) class I molecules.
| Peptides |
HLA molecule |
|||||||
|---|---|---|---|---|---|---|---|---|
| Position | Sequence | A1/B18 | A2 | A3/11 | A24 | B7/35/51 | B27 | B44 |
| 15–22 | RPRKLPQL | 10−9 | ||||||
| 18–26 | KLPQLCTEL | 10−4 | ||||||
| 19–26 | LPQLCTEL | 10−5 | ||||||
| 21–30 | QLCTELQTTI | 10−5 | ||||||
| 24–33 | TELQTTIHDI | 10−5 | ||||||
| 26–34 | LQTTIHDII | 10−5 | ||||||
| 46–55 | RREVYDFAFR | 10−7 | ||||||
| 49–57 | VYDFAFRDL | 10−9 | ||||||
| 50–57 | YDFAFRDL | 10−6 | ||||||
| 52–60 | FAFRDLCIV | 10−4 | 10−6 | |||||
| 54–61 | FRDLCIVY | 10−4 | 10−4 | 10−4 | ||||
| 59–67 | IVYRDGNPY | 10−6 | ||||||
Binding capacities of peptides to immunopurified HLA class I molecules are expressed in M and have been evaluated from at least three independent experiments.