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. 2010 Jan;159(1):73–81. doi: 10.1111/j.1365-2249.2009.04045.x

Fig. 1.

Fig. 1

Expression of Toll-like receptor (TLR)-4 in peripheral blood mononuclear cells in patients with immunoglobulin A nephropathy (IgAN). Percentage of cells positive for surface TLR-4 staining for CD14+cells. Fluorescence activated cell sorter (FACS) analysis. Isotype control: appropriate isotype controls. Healthy controls: 40 samples from 40 healthy subjects. IgAN all samples: 74 samples from 47 patients. IgAN individual patients: first sample obtained from 47 patients during the follow-up. Mean fluorescence intensity (log MFI) of surface TLR-4 staining for CD14+ cells (FACS). Isotype control: appropriate isotype controls. Healthy controls: 40 samples from 40 healthy subjects. IgAN all samples: 74 samples from 47 patients. IgAN individual patients: first sample obtained from 47 patients during the follow-up. Semiquantitative analysis of TLR-4 mRNA in peripheral blood mononuclear cells expressed as TLRs mRNA fold changes to the reference mRNA (reverse transcription–polymerase chain reaction, Taqman). Healthy controls: 40 samples from 40 healthy subjects. IgAN all samples: 74 samples from 47 patients. IgAN individual patients: first sample obtained from 47 patients during the follow-up. P: significance of the difference between groups.