Table 2.
Levels of complement components in sera from wild-type (WT) and complement-deficient mice.
Complement components† | |||||
---|---|---|---|---|---|
Mice | C1q | C3 | C4 | Factor B | Factor D |
WT | 0.80 ± 0.06 | 1.63 ± 0.10 | 0.37 ± 0.06 | 0.91 ± 0.05 | 1.85 ± 0.02 |
Df−/− | 0.90 ± 0.11 | 2.11 ± 0.09* | 0.26 ± 0.08 | 1.20 ± 0.07** | < 0.10 |
MBL−/−/Df−/− | 0.86 ± 0.09 | 1.65 ± 0.04 | 0.19 ± 0.05 | 1.05 ± 0.05 | < 0.10 |
C1q−/−/Df−/− | < 0.15 | 2.27 ± 0.07*** | < 0.10**** | 0.97 ± 0.04 | < 0.10 |
P < 0·004,
P < 0·005,
P < 0·0003,
P < 0·0001, each in comparison to WT.
The data are expressed as optical density units with mean ± standard error of the mean based on n = 6.