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. 2009 Sep 30;29(39):12332–12342. doi: 10.1523/JNEUROSCI.2036-09.2009

Figure 5.

Figure 5.

Heterologous expression of Opn4L and Opn4S suggests that both variants can form a sensory photopigment. Representative whole-cell patch-clamp recording from Neuro-2A cells transfected with Opn4L (A) or Opn4S (B), in the presence of 9-cis-retinal. Monochromatic light stimuli 420 nm and 480 nm (presented for 10 s at 8 × 1014 photons · cm−2 · s−1) evoke a stimulus-dependent inward current. Holding potential, −50 mV. No differences in amplitude of responses, kinetics, or spectral sensitivity were observed between Opn4L and Opn4S.