Fig 3.

Sample axial sections from MD maps (left) and CST profiles (right) from 3 individuals with MS at 2 different time points (red, earlier; green, later). The mean (black) and 90% confidence intervals (gray), derived from a collection of healthy controls, are also displayed. The CST segments are abbreviated as follows: ME indicates medulla; PO, pons; MB, midbrain; IC, internal capsule; CR, corona radiata; SC, subcortical white matter. A, Left tract: A 33-year-old man with RRMS. B, Right tract: A 40-year-old woman with RRMS. C, Left tract: A 49-year-old man with SPMS.