Table 3.
Age and gender adjusted odd ratios (95% confidence intervals) for carriage of individual ‘rare’/’risk’ alleles for normals against gastritis and intestinal metaplasia patient groups.
SNP Locus | Odds ratio (95% confidence interval) | |
---|---|---|
Gastritis (n=91) | Intestinal metaplasia (n=63) | |
TLR 4 +896 G+ | 1.12 (0.49, 2.52) | 1.33 (0.49, 3.59) |
TLR 4 +936 T+ | 0.97 (0.44, 2.11) | 0.99 (0.38, 2.63) |
TNF -238 A+ | 1.32 (0.52, 3.4) | 0.26 (0.05, 1.34) |
TNF -308 A+ | 1.65 (0.9, 3.02) | 1.32 (0.62, 2.83) |
IL-1B -31 C+ | 0.72 (0.4, 1.28) | 0.83 (0.41, 1.67) |
IL-1B -511 T+ | 0.75 (0.42, 1.34) | 0.88 (0.43, 1.77) |
IL-1B +3954 T+ | 0.74 (0.41, 1.34) | 0.97 (0.47, 1.98) |
IL-1RN +2018 C+ | 0.74 (0.41, 1.34) | 0.81 (0.39, 1.67) |
IL-10 -592 A+ | 1.58 (0.86, 2.91) | 1.42 (0.68, 2.94) |
IL-10 -819 T+ | 1.47 (0.81, 2.68) | 1.41 (0.68, 2.91) |
IL-10 -1082 A+ | 0.92 (0.46, 1.84) | 1.15 (0.46, 2.83) |
IL-10 ATA/ATA haplotype | 1.65 (0.38, 7.22) | 0.9 (0.09, 9.63) |