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EGR1 expression in hippocampal neurons. Deparaffinized hippocampal sections from control monkeys (A, B) and monkeys with SIVE (C, D) were immunohistochemically stained for EGR1 content by immunohistochemistry. Compared with control sections, staining of sections from SIVE monkeys is less intense and includes fewer heavily stained cells. Quantification (see Materials and Methods) revealed a 42% reduction of EGR1 in SIVE relative to control (p = 0.014).
