Figure 2.
The secondary structure and overall fold of T. maritima TM1254. The core globular domain, shown in the right half of the figure, consists of six β-strands (yellow arrows), six α-helices (red cylinders) and three 310-helices. The cap domain, shown on the left, consists of four α-helices and has a larger isotropic B factor than the core domain, signifying greater flexibility for this part of the structure. The overall fold is consistent with the identification of TM1254 as a member of the HAD hydrolase family.