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. Author manuscript; available in PMC: 2010 May 11.
Published in final edited form as: Arch Intern Med. 2009 May 11;169(9):832–842. doi: 10.1001/archinternmed.2009.60

Table 2.

ALLHAT Findings in Participants with the Metabolic Syndrome

RR (95% CI) vs. Diuretic


Non Fatal MI /
Fatal CHD
All-Cause
Mortality
CCHD Stroke HF CCVD ESRD

Participants without MetS
α-Blocker 1.00 (0.82-1.22) 0.99 (0.86-1.15) 1.14 (0.99-1.31) 1.19 (0.92-1.55) 1.91 (1.53-2.38) 1.17 (1.05-1.29) 0.81 (0.44-1.49)
ACEI 1.02 (0.88-1.20) 1.02 (0.91-1.14) 1.07 (0.96-1.21) 1.20 (0.97-1.48) 1.02 (0.83-1.25) 1.07 (0.98-1.17) 0.76 (0.48-1.21)
CCB 1.05 (0.90-1.22) 0.93 (0.83-1.04) 1.03 (0.92-1.16) 1.04 (0.83-1.29) 1.45 (1.20-1.75) 1.05 (0.96-1.15) 0.81 (0.51-1.26)

Participants with MetS
α-Blocker 1.11 (0.96-1.28) 1.08 (0.95-1.22) 1.06 (0.96-1.17) 1.31 (1.08-1.58) 1.83 (1.57-2.14) 1.23 (1.14-1.33) 1.18 (0.79-1.77)
ACEI 1.01 (0.90-1.13) 1.01 (0.93-1.12) 1.04(0.96-1.14) 1.09 (0.93-1.28) 1.28 (1.12-1.47) 1.14 (1.06-1.21) 1.22 (0.92-1.63)
CCB 0.95 (0.84-1.07) 0.97 (0.88-1.06) 1.00(0.92-1.04) 0.87 (0.74-1.04) 1.32 (1.15-1.51) 1.05 (0.98-1.12) 1.27 (0.96-1.68)

Non-diabetic Participants with MetS
α-Blocker 1.15 (0.91-1.44) 1.10 (0.89-1.36) 1.07 (0.92-1.25) 1.34 (0.97-1.84) 1.86 (1.44-2.41) 1.24 (1.10-1.39) 0.86 (0.40-1.83)
ACEI 1.05 (0.88-1.27) 1.04 (0.89-1.22) 1.04(0.89-1.22) 1.22 (0.94-1.58) 1.31 (1.04-1.64) 1.19 (1.07-1.32) 1.08 (0.61-1.91)
CCB 0.96 (0.79-1.16) 0.98 (0.83-1.15) 1.01(0.88-1.15) 0.84 (0.62-1.13) 1.09 (0.85-1.38) 1.03 (0.92-1.14) 0.69 (0.36-1.36)

Black Participants with MetS
α-Blocker 1.18 (0.87-1.58) 1.09 (0.87-1.35) 1.15 (0.93-1.41) 1.49 (1.09-2.03) 1.88 (1.42-2.47) 1.37 (1.19-1.58) 1.17 (0.62-2.22)
ACEI 1.17 (0.95-1.47) 1.14 (0.97-1.34) 1.19 (1.01-1.40) 1.37 (1.07-1.76) 1.49 (1.17-1.90) 1.24 (1.09-1.40) 1.70 (1.13-2.55)
CCB 0.96 (0.76-1.21) 1.02 (0.86-1.20) 1.09 (0.92-1.29) 1.01 (0.77-1.33) 1.50 (1.18-1.90) 1.14 (1.00-1.29) 1.50 (0.99-2.28)