Table 3.
Ethnicity | AA Case/Ctrl |
AC Case/Ctrl |
CC Case/Ctrl |
ORAC | ORCC | ORC |
---|---|---|---|---|---|---|
African Americans |
90/117 | 23/20 | 0/1 | 1.50 (0.74,3.04) |
0.00 (0.00,22.90) |
1.31 (0.68,2.52) |
Asians | 86/161 | 296/318 | 167/120 | 1.74 (1.27,2.39) |
2.61 (1.81,3.76) |
1.54 (1.30,1.83) |
Caucasians | 201/259 | 132/83 | 10/6 | 2.05 (1.45,2.89) |
2.15 (0.70,6.77) |
1.80 (1.35,2.41) |
3 Replication Samples (MH) |
1.83 (1.48,2.27) |
2.50 (1.80,3.48) |
1.59 (1.38,1.83)* |
|||
All Samples (MH) |
1.94 (1.68,2.25) |
2.55 (1.92,3.38) |
1.69 (1.52,1.88)** |
χ2 = 42.9, P=5.9×10−11
χ2 = 94.2, P=2.8×10−22
Note: ORAC is the odds ratio for genotype AC versus AA; ORCC is the odds ratio for genotype CC versus AA; ORC is the odds ratio for allele C versus A.