Table 1.
Clinical characteristics of patients with and without LIC after 1st ICD shock
| Characteristic | LIC (+) [n = 106] | LIC (−) [n = 204] | P |
|---|---|---|---|
| Mean age ±SD, y | 59.9±11.7 | 61.5±14.9 | 0.534 |
| Male, n(%) | 74(69.8) | 145(79.9) | 0.816 |
| African Americans, n (%) | 20(18.8) | 28(15.9) | 0.422 |
| Ischemic CM with MI history, n (%) | 72(68.8) | 115(64.6) | 0.389 |
| Primary prevention of SCD, n(%) | 82(77.4) | 163(79.9) | 0.602 |
| Single-chamber ICD, n(%) | 83(78.3) | 92(45.1) | < 0.0001 |
| LVEF at ICD implantation ±SD, % | 33.4±11.6 | 32.8±12.2 | 0.797 |
| NYHA class I, n (%) | 19 (18.4) | 54 (26.3) | 0.699 |
| NYHA class III, n (%) | 20(18.8) | 35(19.5) | 0.946 |
| Diabetes mellitus, n (%) | 46(43.8) | 62(34.6) | 0.197 |
| Hypertension, n (%) | 89(85.4) | 119(67.1) | 0.016 |
| CABG, n (%) | 37(35.4) | 62(34.6) | 0.535 |
| PTCA, n (%) | 37(35.4) | 53(29.6) | 0.312 |
| Beta blockers, n (%) | 87(83.3) | 160(90.1) | 0.195 |
| Digoxin, n(%) | 41(38.4) | 56(27.6) | 0.046 |
| Aldosterone antagonists, n(%) | 50(47.2) | 53(26.1) | <0.0001 |
| Nitrates, n(%) | 21(19.8) | 42(20.7) | 0.856 |
| Class III antiarrhythmics, n(%) | 85(80.2) | 154(75.5) | 0.350 |
| VT/VF with appropriate ICD shocks, n(%) | 29(27.4) | 49(24.0) | 0.465 |
| Renal failure, n (%) | 13(12.5) | 41(23.2) | 0.102 |
| History of atrial fibrillation, n(%) | 24(22.6) | 48(23.5) | 0.633 |